Enter a list of protein names, UniProt accessions, UniProt entry names, or protein names and amino acid positions for the "Inputs" field. The inputs
can be comma-separated or multiple-line format. For amino acid positions with a mutation, the format should be in <Protein_Name>:<Original_Residue><Position><Mutated_Residue>
(MTOR:A8S). It can be comma-separated or multiple-line format (case-senstive).
Select an organism from the select menu. The protein identitifiers have to match with the organism selected.
Click the "Submit" button
Once submitted, an excel like table and image of the first protein in the table will be generated on a new
page.
Click on an isoform identifier to view an isoform and its features.
The disrupted features will be highlighted in red and marked as "disrupted" in the "Status" column.
Enter a protein name for "Protein Name" field. Select an organism from the select menu. If radio button for "Show Isoforms" is "Yes", a list of isoform IDs will be display in a drop down menu based on the user's protein and organism input selections. By default, "canonical" is the selected. Users can then enter a list of protein features that they want to display in the viewer in a <coordinate>:<feature_name> format.
Click on the "Submit" button
Once submitted, a protein feature viewer will be generated on the buttom of the page.
Users can view their custome features under the "Custom Features" category.
Supported sequence annotations
This tool extracts sequence features based on Gene(s) or Gene
position(s) from Human UniProt. For the "Search and Visualize Features" option, the
input takes the Gene Symbol(s) or Gene Position(s) in a list or csv format. A user can
select the name of feature(s) he or she wants to extract. If no
feature type is selected, then the tool will return all the
sequence features for that gene or affected by that position. When entering Gene Position(s),
the input takes the form of <Gene_symbol>:<Original_Residue><Position><Mutated_Residue>
(for example: MTOR:A8S). This option will return all or selected
features that are affected by the mutation(s).